Experimental and theoretical studies of vessel contrast-to-noise ratio in intracranial time-of-flight MR angiography
✍ Scribed by Yiping P. Du; Dennis L. Parker; Wayne L. Davis; Guang Cao; Henry R. Buswell; K. Craig Goodrich
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 977 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
CNR studies were performed for human intracranial vessels in 3D Iu[RA data sets. The CNR dependency of different imaging parameters, such as flip angle, fleld of view, echo time. repetition time, and echo readout symmetry. was studied for vessels in the region of the circle of WiWs. A theoretical model was developed for MR vascular imaging based on the Bloch equations and Fourier imaging theory. This model predicts the lUR image intensity of vessels from basic subject parameters. such as the relaxation times of blood and stationary t h u e . vessel dimension, and flow velocity, and the parameters of the imaging technique, such as flip angle, voxel volume, repetition time, and echo time. For most experiments, the model was found to fit the experimental results well. The validity of this model allows the optimitation of imaging parameters to maximh vessel CNR in M R angiography. Index terms: MR angiography Contrast-to-noise ratio -Flow imaging -Tlme-of-flght MRA. Multiple overlapping thin slab acquisition (MOTSA) -Bloch equations JlyIIu 1 -1:9%108 Abbrevhtione: MRA = magnetic resonance angiography. MOTSA = multi- ple overlapping thin slab acquisition, h4' TC = magnetization transfer contrast, ZFI = Zero-filled interpolation. CNR = contrast-to-noise ratio, FOV = field of view. TE = echo time, TR = repetition time, TOF = time-of-flight. RMSV = root-mean-squarevarlatIon. MCA = middle cerebral artery, VOV = volume of voxel.