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Experimental and Clinical Pharmacokinetics of Amitryptiline: Comparative Analysis

โœ Scribed by Kukes, V. G. (author);Kondratenko, S. N. (author);Savelyeva, Marina I. (author);Starodubtsev, A. K. (author);Gneushev, E. T. (author)


Book ID
106358303
Publisher
Springer US
Year
2009
Tongue
English
Weight
300 KB
Volume
147
Category
Article
ISSN
0007-4888

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The pharmacokinetics of etintidine (E), a potent HZ blocker, were studied in 12 normal, fasted subjects, The subjects received five ascending doses of E HCl in capsules at 72-h intervals. Blood and urine samples were collected and the plasma and urine levels of E were determined by HPLC. Following o