Experimental allergic encephalomyelitis (EAE)-changes in structure and proliferation in rat lymph nodes after sensitization with guinea-pig and bovine basic myelin protein

Prevention of experimental allergic ence

Prevention of experimental allergic encephalomyelitis in lewis rats with peptide 68-88 of guinea pig myelin basic protein

✍ Dr. Frank C.-H. Chou; C.-H. Jen Chou; Robert B. Fritz; Robert F. Kibler 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 374 KB 👁 1 views

## Abstract The highly encephalitogenic guinea pig peptide 68‐88 has been used to develop an effective and reproducible model of protection in the Lewis rat. Doses as low as 0.1 nmol of peptide protected 70% of rats when injected intraperitoneally six and four weeks prior to challenge with 0.05 nmo