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Experience With Orthoclone OKT3 Monoclonal Antibody in Liver Transplantation

โœ Scribed by Gordon, Robert D.; Tzakis, Andreas G.; Iwatsuki, Shunzaburo; Todo, Satoru; Esquivel, Carlos O.; Marsh, J. Wallis; Stieber, Andrei; Makowka, Leonard; Starzl, Thomas E.

Book ID
124142286
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
355 KB
Volume
11
Category
Article
ISSN
0272-6386

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## Abstract Orthoclone OKT3 is a murine monoclonal antibody that blocks the generation and function of T lymphocytes. It has been shown to be effective in reversing acute cellular rejection in solid organ transplants. However, potential development of antimurine antibodies restricts the duration th