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Experience with GM-CSF in the treatment of solid tumors

✍ Scribed by M. Wolf; K. Havemann


Book ID
105282905
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
635 KB
Volume
20
Category
Article
ISSN
0300-8126

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We explored the potential therapeutic benefit of introducing GM-CSF, IFN-β₯ or a combination of both factors into CT26 tumor cells. CT26 cells secreting either GM-CSF or IFN-β₯ exhibited delayed tumorigenicity; however, cells expressing both GM-CSF and IFN-β₯ did not form tumors. Even when wild type CT