We have described the advantages and disadvantages of using the rat epigastric free flap as a means of studying transplantation phenomena. The study comprises 20 epigastric free flap autografts in rats. After l V 2 years of working on the model, we achieved a 75% success rate in the last 20 consecut
Experience with epigastric free flap allograft in the rat
โ Scribed by Leonard K. Ruby; Mark Greene; Giovanni Risitano
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 97 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0738-1085
No coin nor oath required. For personal study only.
โฆ Synopsis
We report our continuing experience with the rat epigastric free vascularized flap as a transplant model. Four groups of ten pure-bred rats underwent transplantation of epigastric vessel based skin flaps. The flaps were immediately revascularized in the recipient animal and the results recorded. No immunologic manipulation was performed. Rejection and acceptance of the flaps occurred according to known genetic predictions in these 40 procedures. This study will serve as a control for immunologic manipulation experiments.
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