Experience with domino or sequential liver transplantation in familial patients with amyloid polyneuropathy
✍ Scribed by J Figueras; D Parés; M Munar-Qués; J Torras; J Fabregat; A Rafecas; E Ramos; C Lama; J Busquets; A Dalmau; A Sabate; E Jaurrieta
- Book ID
- 117231711
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 44 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0041-1345
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Liver transplantation (LT) is the only curative option for patients with familial amyloid polyneuropathy (FAP) at present. Twenty patients with FAP underwent LT between May 1998 and June 2007. Transthyretin mutations included predominantly the Val30Met mutation but also 10 other mutations. Seven pat
Familial amyloidotic polyneuropathy (FAP) patients present adrenergic cardiac input blockade secondary to amyloid deposits and sympathetic neuropathy. Consequently, their capacity to compensate for hemodynamic changes is limited. To avoid hemodynamic disturbances in sequential liver transplants, a s