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Expeditious Enantioselective Biomimetic Synthesis of the Nitraria Alkaloids (+)-Isonitramine and (−)-Sibirine

✍ Scribed by David François; Marie-Christine Lallemand; Mohamed Selkti; Alain Tomas; Nicole Kunesch; Henri-Philippe Husson


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
72 KB
Volume
37
Category
Article
ISSN
0044-8249

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The securinega alkaloids are a family of approximately 20 tetracyclic compounds produced by several Securinega and Phyllanthus species of the Euphorbiaceae plant family. The major securinega alkaloid is securinine (1), isolated from the leaves of Securinega suffruticosa. Its enantiomer, virosecurin