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Expectation of LET∞ for a tritium beta particle

✍ Scribed by Toshifumi Saigusa; Sakae Shimizu

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
186 KB
Volume
280
Category
Article
ISSN
0168-9002

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📜 SIMILAR VOLUMES

A convenient method for the specific tri
A convenient method for the specific tritium labelling of beta-adrenoceptor antagonists
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## Abstract The specific tritium labelling of beta‐adrenoceptor antagonists of the general structure ArOCH~2~CH(OH)CH~2~NHR is described. The tritium label is introduced in the 2‐position in the aminohydroxypropoxy side‐chain starting from ArOCH, an intermediate in the synthesis of the unlabelled c

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## Abstract Two cardioselective beta‐adrenoceptor antagonists: dl‐acetanalide‐4′‐[3‐(isopropylamino)‐2‐hydroxypropoxy] (“practolol”), and dl‐chloroacetanilide‐4′‐[3‐(isopropylamino) ‐2‐hydroxypropoxy] (“chloropractolol”), labeled with tritium at positions 3′ and 5′of the aromatic ring were prepared