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Expansion of normal and leukemic human hematopoietic stem/progenitor cells requires Rac-mediated interaction with stromal cells

✍ Scribed by Marjan Rozenveld-Geugien; Inge O. Baas; Djoke van Gosliga; Edo Vellenga; Jan Jacob Schuringa


Book ID
113616328
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
969 KB
Volume
35
Category
Article
ISSN
0301-472X

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## Abstract An efficient and practical __ex vivo__ expansion methodology for human hematopoietic stem/progenitor cells (HSPCs) is critical in realizing the potential of HSPC transplantation in treating a variety of hematologic disorders and as a supportive therapy for malignant diseases. We report