The cholecystokinin A receptor (CCK-AR) modulates CCK-stimulated dopamine release in the posterior nucleus accumbens, and its gene is mapped to 4p15.2-15.1 with the dopamine receptor 5 (DR5) gene. We speculated that alterations in the CCK-AR lead to an increase in dopamine release, which may in turn
โฆ LIBER โฆ
Exon/intron boundaries, novel polymorphisms, and association analysis with schizophrenia of the human synaptic vesicle monoamine transporter (SVMT) gene
โ Scribed by Kunugi, H; Ishida, S; Akahane, A; Nanko, S
- Book ID
- 110059340
- Publisher
- Nature Publishing Group
- Year
- 2001
- Tongue
- English
- Weight
- 148 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1359-4184
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Genetic variations in the 5-untranslated region and the coding region of the CCK-B receptor (CCK-BR) gene were investigated in healthy controls. Novel variants (-215 CโA, Leu37Phe, Arg319Glu) were found in addition to the mutations (Val125Iso, His207His, Arg215His, 2491 CโA) reported previously. In