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Exon Structure and Flanking Intronic Sequences of the Human RET Proto-oncogene

✍ Scribed by I. Ceccherini; R. Bocciardi; Y. Luo; B. Pasini; R. Hofstra; M. Takahashi; G. Romeo

Book ID
115573764
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
363 KB
Volume
196
Category
Article
ISSN
0006-291X

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A novel polymorphism in the coding seque
A novel polymorphism in the coding sequence of the human RET proto-oncogene
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A novel polymorphism in the coding sequence of the human RET proto-oncogene is described. The RET proto-oncogene maps to chromosome 10q11.2, and is involved in multiple endocrine neoplasia (MEN 2A, MEN 2B), familial medullary thyroid carcinoma and Hirschsprung's disease.