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Exogenous prostaglandin E2 inhibits TPA induced matrix metalloproteinase-9 production in MCF-7 cells

✍ Scribed by F Renò; G Baj; N Surico; M Cannas


Book ID
113864869
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
212 KB
Volume
73
Category
Article
ISSN
0090-6980

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✍ Christine Jespersen; Anke Doller; El-Sayed Akool; Malte Bachmann; Roswitha Mülle 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 379 KB

## Abstract Matrix metalloproteinase‐9 (MMP‐9) is implicated in the invasion and metastasis of breast cancer cells. We investigated the modulatory effects of nitric oxide (NO) on the 12‐__O__‐tetradecanoylphorbol 13‐acetate (TPA)‐induced MMP‐9 expression in MCF‐7 cells. Different chemical NO donors