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Exogenous Methemoglobin as a Cyanide Antidote in Rats

โœ Scribed by Garry W. Boswell; Daniel E. Brooks; Alison J. Murray; Angelia A. Doye; David J. Disselhorst; Cheryl L. Chin; Charles B. Clifford


Book ID
114421036
Publisher
Springer US
Year
1988
Tongue
English
Weight
818 KB
Volume
05
Category
Article
ISSN
0724-8741

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Antidotes for cyanide (CN) intoxication include the use of sulfane sulfur donors (SSDs), such as thiosulfate, which increase the conversion of CN to thiocyanate by the enzyme rhodanese. To develop pretreatments that might be useful against CN, SSDs with greater lipophilicity than thiosulfate were sy