Exo- and endo-palladacycles derived from (4R)-phenyl-2-oxazolines
β Scribed by Olga N Gorunova; Kristopher J Keuseman; Bryce M Goebel; Nadezhda A Kataeva; Andrey V Churakov; Lyudmila G Kuz'mina; Valery V Dunina; Irina P Smoliakova
- Book ID
- 108187848
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 437 KB
- Volume
- 689
- Category
- Article
- ISSN
- 0022-328X
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## Abstract The reactions of 2__exo__β and 2__endo__βnorbornyl bromide (**1e** and **2e**, respectively) in 90% ethanol with a large excess of potassium hydroxide, and of 2__exo__βnorbornyl __p__βtoluenesulfonate **(1g)** with excess sodium thiophenolate in methyl cellosolve, have been studied. The
The allylboron reagent 4 prepared .from endo-2-phenyl-exo-2,3-bornanediol reacts with achiral aldehydes to give homoallylic alcohols in good yields and high enantioselectivity (70-85% ee). This new reagent also exhibits good levels of matched and mismatched diastereoselection in reaction with chiral