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Existing and emerging mitochondrial-targeting therapies for altering Parkinson's disease severity and progression

✍ Scribed by Pienaar, Ilse S.; Chinnery, Patrick F.

Book ID
118743524
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
881 KB
Volume
137
Category
Article
ISSN
0163-7258

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## Abstract Parkinson's disease (PD) is marked by widespread neurodegeneration in the brain in addition to a selective yet prominent and progressive loss of nigrostriatal dopaminergic neurons. Of the multiple theories suggested in the pathogenesis of PD, mitochondrial dysfunction takes a center sta