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Excretion of (sulfated) steroids in the urine and excretion of cholesterol sulfate in the feces of boys with recessive X-linked ichthyosis

✍ Scribed by A. Marinkovic-Ilsen; A. Ende; B. G. Wolthers

Publisher: Springer-Verlag
Year: 1984
Tongue: English
Weight: 446 KB
Volume: 276
Category: Article
ISSN: 0340-3696
DOI: 10.1007/bf00413356

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✦ Synopsis

The excretion of sulfated steroids was investigated in the urine and feces of six boys aged 9 months to 7 years and 10 months who had recessive X-linked ichthyosis. Profiles of urinary total steroids as well as sulfated steroids were normal. Cholesterol sulfate excretion in the urine was not elevated. In the feces 2-20% of total cholesterol was cholesterol sulfate, whereas in the feces of 28 healthy children no cholesterol sulfate was demonstrable. In the 6 patients total cholesterol excretion (500-2,500 gmol/kg feces) was also elevated in comparison with the 28 healthy controls (150-700 gmol/kg feces, mean 365 gmol/kg feces)

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