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Excretion of benzo[a]pyrene-Gua adduct in the urine of benzo[a]pyrene-treated rats

✍ Scribed by Herman Autrup; Tina Seremet


Book ID
113136933
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
543 KB
Volume
60
Category
Article
ISSN
0009-2797

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Excretion of 3-hydroxy-benzo(a)pyrene an
✍ F. J. Jongeneelen; Ch. M. Leijdekkers; R. P. Bos; J. L. G. Theuws; P. Th. Hender πŸ“‚ Article πŸ“… 1985 πŸ› John Wiley and Sons 🌐 English βš– 463 KB πŸ‘ 1 views

3-hydroxy-benzo(a)pyrene (3-OH-B(a)P) and mutagenic activity in rat urine were determined after the oral administration of benzo(a)pyrene given in three repeated doses of 10, 20 and 50 pmol kg-'. The procedure for the determination of 3-OH-B(a)P consisted of enzymic hydrolysis, separation and HPLC-a