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Excitotoxicity of AMPA and kainate receptor activation and desensitization in cultured neurons

✍ Scribed by A. Schousboe; J.B. Jensen; D.S. Pickering

Book ID
119578116
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
145 KB
Volume
5
Category
Article
ISSN
0928-4680

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We investigated the role of kainate (KA) receptor activation and desensitization in inducing the increase in the intracellular free Ca(2+) concentration ([Ca(2+)](i)) in individual cultured rat hippocampal neurons. The rat hippocampal neurons in the cultures were shown to express kainate receptor su