Contribution of a mitochondrial pathway
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Dae-Won Seo; Maria-Leonor Lopez-Meraz; Suni Allen; Claude Guy Wasterlain; Jerome
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Article
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2009
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John Wiley and Sons
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English
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## Abstract It is traditionally thought that excitotoxic necrosis is a passive mechanism that does not require the activation of a cell death program. In this study, we examined the contribution of the cytochrome cβdependent mitochondrial death pathway to excitotoxic neuronal necrosis, induced by e