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Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95

✍ Scribed by Gascón, S; Sobrado, M; Roda, J M; Rodríguez-Peña, A; Díaz-Guerra, M


Book ID
110060291
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
546 KB
Volume
13
Category
Article
ISSN
1359-4184

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✍ Lixin Sun; Michael T. Shipley; Michael S. Lidow 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB 👁 2 views

Quantitative reverse transcriptase -polymerase chain reaction was used to analyze the relative expressions of NR1, NR2A, NR2B, NR2C, NR2D, and NR3 subunits of the NMDA receptor in the piriform, entorhinal, visual, and motor cortices as well as in the olfactory bulb of adult rat. The analysis detecte