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Excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices

✍ Scribed by Avital Schurr; Ralphiel S Payne; Michael T Tseng; Evelyne Gozal; David Gozal

Book ID: 117471866
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 153 KB
Volume: 307
Category: Article
ISSN: 0304-3940
DOI: 10.1016/s0304-3940(01)01937-1

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## Abstract Excitotoxicity and cell death induced by glutamate are involved in many neurodegenerative disorders. We have previously demonstrated that excitotoxicity induced by millimolar concentrations of glutamate in hippocampal slices involves apoptotic features and glutamate‐induced glutamate re