Smooth muscle cells squeeze Ihe blood back to your heart, raise the hackles on your neck and change the F-stop of your eyes. The past year has provided penetrating new insights into their mechanism of contraction.
Excited hydrogen bonds in the molecular mechanism of muscle contraction
โ Scribed by S.V. Bespalova; K.B. Tolpygo
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 467 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0022-5193
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โฆ Synopsis
The mechanism of muscle contraction is considered. The hydrolysis of an ATP molecule is assumed to produce the excitation of hydrogen bonds A--H..-B between electronegative atoms A and B, which are contained in the myosin head and actin filament. This excitation energy ef depends on the interatomic distance AB = R and generates the tractive force f= -Oef/OR, that makes atoms AB approach each other. The swing of the myosin head results in macroscopic mutual displacement of actin and myosin polymers. The motion of the actin filament under the action of this force is studied. The conditions under which a considerable portion of the excitation energy converts into the potential tension energy of the actin filament are analysed, and the probability of higher muscle efficiency existence is discussed.
๐ SIMILAR VOLUMES
Ab initio calculations for the interacting system of lower excited states of planar and bent HzCO with B?O have been carried out with a minimum basis set, using the recently proposed electron-hole potential method The blue shifts of the n-z\* transition are evaiuated as I100 and 142Q cm-\* ' .or th
HX bonds are often elongated upon forming a hydrogen-bonded complex. Concomitantly, the HX stretching frequency undergoes a red-shift. Ab initio calculations for several dimers of HF suggest that an opposite behavior may sometimes arise for the proton acceptor, namely, the bond that is adjacent to t