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EXCITATORY AND INHIBITORY EFFECTS OF SECOND-GENERATION CHOLINESTERASE INHIBITORS ON RAT GASTROINTESTINAL TRANSIT

✍ Scribed by DANIELA BRAIDA; WALTER VIRAG; FRANCESCO OTTONELLO; MARIAELVINA SALA


Book ID
118770819
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
402 KB
Volume
41
Category
Article
ISSN
1043-6618

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Second generation cholinesterase inhibit
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## Abstract L‐Huperzine‐A (Hup‐A), a natural cholinesterase inhibitor (ChEI) derived from the Chinese herb Huperzia serrata, was administered systemically (i.p.) or locally through the microdialysis probe into the rat cortex. Systemic Hup‐A significantly increased acetylcholine (ACh) levels above b