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Excitatory Amino Acids Differentially Regulate the Expression of GDNF, Neurturin, and Their Receptors in the Adult Rat Striatum

✍ Scribed by Sònia Marco; Anna M. Canudas; Josep M. Canals; Núria Gavaldà; Esther Pérez-Navarro; Jordi Alberch

Book ID
115607686
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
407 KB
Volume
174
Category
Article
ISSN
0014-4886

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Differential regulation of GDNF, neurtur
Differential regulation of GDNF, neurturin, and their receptors in primary cultures of rat glial cells
✍ Séverine Rémy; Philippe Naveilhan; Philippe Brachet; Isabelle Neveu 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 252 KB

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) bind to GFR alpha-1 and GFR alpha-2 receptors, respectively, and their neurotrophic activity is mediated by the tyrosine kinase receptor, Ret. All these molecules were found to be expressed in primary cultures of rat glial cells,