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Excitatory amino acid neurotoxicity: In vitro models, mechanisms of action and effects of ganglioside GM1

✍ Scribed by Milani, D.; Facci, L.; Morandi, A.; Leon, A.; Skaper, S.D.

Book ID
123412622
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
82 KB
Volume
22
Category
Article
ISSN
1043-6618

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Excitatory amino acid neurotoxicity in cultured retinal neurons: Involvement of N-methyl-D-Aspartate (NMDA) and Non-NMDA receptors and effect of ganglioside GM1
✍ L. Facci; A. Leon; Dr. S. D. Skaper πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 997 KB

Cultures of chicken day 8 embryo retinal cells, essentially free of contaminating non-neuronal elements, were used to examine the neurotoxicity of various excitatory amino acid transmitter receptor agonists. At 7 days in vitro, N-methyl-D-aspartate (NMDA), following 24 hr exposure to 0.1-1.0 mM, des