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Excitatory amino acid neurotoxicity at the N-methyl-d-aspartate receptor in cultured neurons: role of the voltage-dependent magnesium block

โœ Scribed by Jane A. Cox; Paul G. Lysko; Richard C. Henneberry


Book ID
115799527
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
518 KB
Volume
499
Category
Article
ISSN
0006-8993

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Excitatory amino acid neurotoxicity in c
โœ L. Facci; A. Leon; Dr. S. D. Skaper ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 997 KB

Cultures of chicken day 8 embryo retinal cells, essentially free of contaminating non-neuronal elements, were used to examine the neurotoxicity of various excitatory amino acid transmitter receptor agonists. At 7 days in vitro, N-methyl-D-aspartate (NMDA), following 24 hr exposure to 0.1-1.0 mM, des