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Excitatory action of the tetrapeptide tuftsin on activity of albino rats

โœ Scribed by A. A. Kamenskii; L. V. Antonova; N. A. Samoilova; O. M. Galkin; S. M. Andreev; I. P. Ashmarin


Publisher
Springer US
Year
1980
Tongue
English
Weight
318 KB
Volume
90
Category
Article
ISSN
0007-4888

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Incubation of human polymorphonuclear leukocytes (PMNL) or thioglycollate-stimulated mouse peritoneal macrophages with the phagocytosis-stimulating peptide, tuftsin (2.5 X 10(-7) M, at 37 degrees C), caused an increase of 80-90% in intracellular cGMP levels, accompanied by a decrease of 20-25% in in