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Excitability in the adenylate cyclase reaction in Dictyostelium discoideum

✍ Scribed by A. Goldbeter; T. Erneux; L.A. Segel

Book ID
115908404
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
299 KB
Volume
89
Category
Article
ISSN
0014-5793

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Developmentally regulated compartmentali
Developmentally regulated compartmentalization of adenylate cyclase in Dictyostelium discoideum
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Adenylate cyclase of aggregation phase Dictyostelium discoideum is activated by extracellular adenosine 3', 5'-cyclic monophosphate (cAMP), and the cAMP synthesized is secreted. The distribution of the enzyme was determined in sucrose gradients loaded with whole cell lysates. Cell lysates prepared a