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Excision of the mouse Xist gene alters the heterochromatin of the inactive X chromosome and the replication time and DNA stability of both X chromosomes

✍ Scribed by York Marahrens; Silvia Diaz-Perez; Shih-Chang Tsai; David Ferguson

Book ID
116975619
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
45 KB
Volume
295
Category
Article
ISSN
0012-1606

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## Abstract We previously characterized a functional origin of DNA replication at the transcriptional promoter of the human hypoxanthine‐guanine phosphoribosyltransferase (__HPRT__) gene (Cohen et al. [2002] J. Cell. Biochem. 85:346‐356). This origin was mapped using a quantitative PCR assay to eva