✦ LIBER ✦

Excimer laser ablation of fibrocartilage: An in vitro and in vivo study

✍ Scribed by Martin Buchelt; Thanassis Papaioannou; Mike Fishbein; Werner Peters; Clain Beeder; Warren S. Grundfest

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 994 KB
Volume: 11
Category: Article
ISSN: 0196-8092
DOI: 10.1002/lsm.1900110311

No coin nor oath required. For personal study only.

✦ Synopsis

To date, lasers have found only limited applications in orthopedics. We employed a 308 nm XeCl excimer laser for ablation of fibrocartilage, in order to investigate the feasibility of excimer laser assisted meniscectomy.

Experiments were conducted both in vitro and in vivo. For the in vitro study, human menisci, obtained during surgery and autopsy, were irradiated via a 600 m core fiber at radiant expolation rate measurements and histological analysis of the samples were performed. The ablation rates were found to range from 3 pm/pulse to 100 pm/pulse depending on the radiant exposure and/or the applied pressure on the fiber delivery system. Thermographic analysis was also performed during pulsed excimer as well as CW NdYag and CW C 0 2 laser irradiation. Temperatures were lower for excimer laser (T,,, < 65") than CW ND: Yag (T, , , < 210") or CW C 0 2 (T, , , < 202") laser.

For the in vitro study, medial meniscectomy was performed in 15 rabbits with the excimer laser and a CW NdYag laser in the right and left knee res ectively. Excimer laser irradiation was 600 pm core fiber at power outputs between 20 to 40 W for 10 and 20 seconds duration.

The healing response to injury was investigated by histological analysis of the menisci after 1 day, 1, 2, 4, and 8 weeks following the laser procedure. Excimer laser treated menisci showed less inflammatory reaction and noticeable repair with minimal inflammatory response. Carbonization, induced in the Nd:Yag treated menisci remained up to 8 weeks and only minimal healing was observed. The results suggest that, with the development of an appropriate delivery system, excimer laser ablation may be useful in arthroscopic meniscectomy.

sures ranging between 20 mj/mm P and 80 mj/mm2, at 20 Hz. Abperformed at 70 mj/mm P . Nd:Yag irradiation was performed via

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