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Exchange red blood cell pheresis in a pediatric patient with severe complications of sickle cell anemia

✍ Scribed by S. Kleinman; R. Thompson-Breton; D. Breen; C. Hurvitz; D. Goldfinger

Book ID
114437584
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
285 KB
Volume
21
Category
Article
ISSN
0372-1248

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## Abstract Chronic simple hypertransfusion (every 3 to 4 weeks) effectively prevents secondary stroke in children with sickle cell anemia but leads to iron overload despite chelation therapy. Conventional red blood cell exchange (C‐RBCx) has advantages over simple transfusion: no net iron gain and