Periodic knee injections of BMP-7 delay
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Ichiro Sekiya; Tao Tang; Masaya Hayashi; Toshiyuki Morito; Young-Jin Ju; Tomoyuk
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Article
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2009
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Elsevier Science
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English
β 258 KB
## Abstract Strenuous running of rats enhances mechanical stress on the knee, thereby inducing degeneration of articular cartilage. Bone morphogenetic proteinβ7 (BMPβ7) has an inhibitory effect on cartilage degeneration, suggesting its usefulness for human osteoarthritis patients. However, its mode