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Examining the Regulation of Voltage-Dependent S4 Movement in hERG Potassium Channels

✍ Scribed by Cheng, Yen May; Hull, Christina M.; Iwanski, Jessika; Claydon, Tom W.


Book ID
123103045
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
39 KB
Volume
104
Category
Article
ISSN
0006-3495

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The solution structure of the S4–S5 link
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The human ether‐à‐go‐go related gene (hERG) encodes a protein that forms a voltage‐gated potassium channel and plays an important role in the heart by controlling the rapid delayed rectifier K^+^ current (__I__~Kr~). The S4–S5 linker was shown to be important for the gating of the hERG channel. Nucl