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Examining the Impact of Supercoiling on Sequence-Dependent DNA Structure and Flexibility

✍ Scribed by Pedini, Heidi S.; Al-Hashimi, Hashim M.

Book ID: 122098763
Publisher: Biophysical Society
Year: 2012
Tongue: English
Weight: 37 KB
Volume: 102
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2139

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## Abstract CD spectra were obtained for eight synthetic double‐stranded DNA polymers down to at least 175 nm in the vacuum uv. Three sets of sequence isomers were studied: (a) poly[d(A‐C) · d(G‐T)] and poly[d(A‐G) · d(C‐T)], (b) poly[d(A‐C‐C) · d(G‐G‐T)] and poly[d(A‐C‐G) · d(C‐G‐T)], and (c) poly