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Examining polygenic risk of cigarette use in the Detroit Neighborhood Health Study

✍ Scribed by Meyers, Jacquelyn; Galea, Sandro; Aiello, Allison; Uddin, Monica; Wildman, Derek; Koenen, Karestan


Book ID
122314534
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
54 KB
Volume
54
Category
Article
ISSN
1532-8384

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## Abstract Microsomal epoxide hydrolase (mEH) and cytochrome P450 2C9 (CYP2C9) are involved in the bioactivation and detoxification of polycyclic aromatic hydrocarbons (PAHs) derived from tobacco smoke. Two coding‐region __mEH__ variants (Tyr113His, His139Arg) and __CYP2C9__ variants (Arg144Cys, I