𝔖 Bobbio Scriptorium
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Examining methods for calculations of binding free energies: LRA, LIE, PDLD-LRA, and PDLD/S-LRA calculations of ligands binding to an HIV protease

✍ Scribed by Yuk Yin Sham; Zhen Tao Chu; Holly Tao; Arieh Warshel


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
202 KB
Volume
39
Category
Article
ISSN
0887-3585

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✦ Synopsis


found that results of similar quality are obtained by the PDLD/S method and the LRA method. This is significant since the PDLD/S method is much faster than the LRA and LIE methods. However, more studies of the relative accuracy on other systems are needed in order to establish their relative merits.