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Examination of magnesium binding to serum proteins by ultracentrifugal analysis

โœ Scribed by Norman A. Cummings; Edward L. Kuff; Herbert A. Sober


Book ID
107710913
Publisher
Elsevier Science
Year
1968
Tongue
English
Weight
457 KB
Volume
22
Category
Article
ISSN
0003-2697

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A New Data Analysis Method to Determine
โœ Michelle Arkin; J.D. Lear ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 154 KB

In principle, equilibrium analytical ultracentrifugation (AU) can be used to quantify the binding stoichiometry and affinity between small-molecule ligands and proteins in aqueous solution. We show here that heteromeric binding constants can be determined using a data-fitting procedure which utilize