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Exact Tests of Hardy-Weinberg Equilibrium and Homogeneity of Disequilibrium across Strata

✍ Scribed by Daniel J. Schaid; Anthony J. Batzler; Gregory D. Jenkins; Michelle A.T. Hildebrandt


Book ID
117854951
Publisher
American Society of Human Genetics
Year
2006
Tongue
English
Weight
263 KB
Volume
79
Category
Article
ISSN
0002-9297

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Testing for Hardy-Weinberg equilibrium (HWE) is commonly used as a quality control filter in genome-wide scans for markers with experimentally determined genotypes. In contrast, for markers with imputed genotypes, there are post-imputation metrics of quality that can be used as screens but there are