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Exacerbation of systemic inflammation and increased cerebral infarct volume with cardiopulmonary bypass after focal cerebral ischemia in the rat

✍ Scribed by H. Mayumi Homi; Wilbert L. Jones; Fellery de Lange; G. Burkhard Mackensen; Hilary P. Grocott


Book ID
113763645
Publisher
CTSNet
Year
2010
Tongue
English
Weight
243 KB
Volume
140
Category
Article
ISSN
1097-685X

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## Abstract Unfractionated heparin (UH) decreases the extent of infarction after transient focal brain ischemia in the rat and abridges neuroinflammatory damage in patients with acute stroke. This study was aimed at assessing whether controlled and steady heparinemia in plasma can reduce infarct vo