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Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells

โœ Scribed by Florentin-Martial Mbitikon-Kobo; Marc Bonneville; Rafick-Pierre Sekaly; Lydie Trautmann


Book ID
113718034
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
646 KB
Volume
375
Category
Article
ISSN
0022-1759

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The ex vivo expansion of antigen-specific cytotoxic T lymphocyte (CTL) lines is being developed for immunotherapy of viral infections and cancer and is critically dependent on the precise cell expansion and stimulation conditions. In this article, we investigate medium requirements for the developme