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Ex Vivo Assessment of Contractility, Fatigability and Alternans in Isolated Skeletal Muscles

✍ Scribed by Park, Ki Ho; Brotto, Leticia; Lehoang, Oanh; Brotto, Marco; Ma, Jianjie; Zhao, Xiaoli

Book ID
118062184
Publisher
MyJoVE Corporation
Year
2012
Tongue
English
Weight
296 KB
Volume
69
Category
Article
ISSN
1940-087X

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## Abstract Myoblast transfer therapy for Duchenne muscular dystrophy (DMD) largely fails due to cell death and inability of transplanted cells to engraft in diseased muscles. One method attempting to enrich for cell subpopulations is the Hoechst 33342 dye exclusion assay, yielding a side populatio