EWS-FLI-1 and EWS-ERG chimeric mRNAs in
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Kohmei Ida; Shigetoshi Kobayashi; Tomohiko Taki; Ryoji Hanada; Fumio Bessho; Shu
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Article
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1995
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John Wiley and Sons
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French
⚖ 620 KB
The t( I I ;22)(q24;q 12) and t(2 I ;22)(q22;q 12) are specific chromosomal translocations found in the Ewing family of tumors including ES, PNET and Askin tumors. In these translocations, the amino-terminal portion of the EWS gene located in 22q12 fuses to the carboxyl-terminal portion of the FLI-I