## Abstract Studies in hepatocyte cultures indicate that apolipoprotein (apo) B‐100 production is regulated largely by intracellular degradation and the proteasome pathway is a major mechanism for the degradation. In the present study, we have examined the detailed itinerary of apoB degradation thr
✦ LIBER ✦
Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD)
✍ Scribed by Ardythe A. McCracken; Jeffrey L. Brodsky
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 191 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0265-9247
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## Abstract The N‐methyl‐D‐aspartate receptor (NMDAR) is fundamental to normal and pathological functioning of neurons. The receptor subunits are N‐glycosylated proteins synthesized in the endoplasmic reticulum (ER) that fold, mature, and oligomerize as they transit through the secretory pathway. A