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Evolutionary conservation of sequence and secondary structures in CRISPR repeats

✍ Scribed by Victor Kunin, Rotem Sorek, Philip Hugenholtz

Book ID
120702561
Publisher
BioMed Central
Year
2007
Tongue
English
Weight
924 KB
Volume
8
Category
Article
ISSN
1465-6906

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We have attempted to predict the three-dimensional structures of 19 proteins for the CASP3 experiment, each showing less than 25% sequence identity with known structures. Predictions were based on a threading method that aligns the target sequence with the conserved cores of structural templates, as