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Evolutionary conservation of physical and functional interactions between phospholipase D and actin

✍ Scribed by David J Kusner; James A Barton; Chunbo Qin; Xuemin Wang; Shankar S Iyer


Book ID
117042467
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
340 KB
Volume
412
Category
Article
ISSN
0003-9861

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## Abstract The de novo methyltransferase‐like protein, DNMT3L, is required for methylation of imprinted genes in germ cells. Although enzymatically inactive, human DNMT3L was shown to act as a general stimulatory factor for de novo methylation by murine Dnmt3a. Several isoforms of DNMT3A and DNMT3