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Evolutionary conservation of MHC class I and class II molecules—different yet the same

✍ Scribed by Jim Kaufman; Jan Salomonsen; Martin Flajnik


Book ID
115647780
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
809 KB
Volume
6
Category
Article
ISSN
1044-5323

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he allele-specific peptidebinding motifs of major histocompatibility complex (MHC) proteins, originally discovered by pool sequencing of MHC class I-bound peptides 1 , provide a biochemical basis for the phenomenon of MHC restriction of T-cell responses. However, the analysis of class II peptide mot