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Evolutionary appearance of mononucleotide repeats in the coding sequences of four genes in primates

✍ Scribed by Ariane Paoloni-Giacobino; John Richard Chaillet

Book ID
107584990
Publisher
Indian Academy of Sciences
Year
2007
Tongue
English
Weight
228 KB
Volume
86
Category
Article
ISSN
0022-1333

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## Abstract We have systematically retrieved genes with coding mononucleotide repeats from sequence databases and analyzed them for mutations in tumors with high levels of microsatellite instability (MSI‐H). We found somatic frameshift mutations in 7/13 genes previously not analyzed in MSI‐H tumors