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Evolution to eosinophilic leukemia with a t(5:11) translocation in a patient with idiopathic hypereosinophilic syndrome

โœ Scribed by T.J. Yoo; Stephen V. Orman; Shivanand R. Patil; C. Dorminey; S. Needleman; D. Rajtora; N. Graves; L. Ackerman; W.W. Taylor


Book ID
119102808
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
527 KB
Volume
11
Category
Article
ISSN
0165-4608

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A patient with chronic eosinophilic leukemia and a unique complex chromosomal translocation 46,XY,t(3;9;5)(q25;q34;q33) who had elevated blood interleukin-5 is reported. Complete cytogenetic remission was induced by interferon-โฃ after treatment failure with corticosteroids and cytotoxic drugs. Sever