## Abstract Pyruvate kinase exists as two major isozymes in coho salmon. As in mammals and birds, one form is present in the early embryo and maintains a wide tissue distribution in adults. This salmonid type K shows anodal migration during electrophoresis at pH 7.5. The appearance of the second ma
Evolution of the functional properties of pyruvate kinase isozymes: pyruvate kinase L fromRana pipiens
โ Scribed by Paul Fournier; Helga Guderley
- Publisher
- Springer-Verlag
- Year
- 1986
- Tongue
- English
- Weight
- 945 KB
- Volume
- 156
- Category
- Article
- ISSN
- 0174-1578
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## Abstract Two major isozymes of pyruvate kinase that differ in electrophoretic and kinetic properties are found in salmon (__Oncorhynchus kisutch__). Type M occurs in cardiac and skeletal muscle, while type K is the main isozyme of the other tissues. We have been examining the structural and kine
We have compared the kinetic, immunological, and electrophoretic properties of human and canine erythrocyte pyruvate kinase. Both enzymes are allosteric and subject to positive and negative regulation. The allosteric properties of the canine enzyme are more pronounced than those of the human enzyme;
## Abstract Pyruvate kinase occurs as two major forms in coho salmon; the type M isozyme occurs primarily in muscle and heart, but type K has a more generalized tissue distribution, in parallel with the type K isozyme in other vertebrate systems. In order to assess the evolutionary relationships am